Diabetic peripheral neuropathy (DPN) is one of the most common secondary diseases of diabetes mellitus. Early diagnosis and holistic treatment strategies, including targeted supplementation with essential biofactors, can slow down the progression of the disease and improve quality of life.

Zinc plays an important role in the prevention and treatment of acne vulgaris. The essential biofactor has an anti-inflammatory effect, regulates sebum production and supports the skin barrier.

Vitamin D influences the regulation of estrogen and progesterone through its vitamin D receptors in various tissues. Estrogen is also involved in the regulation of vitamin D metabolism. Studies show that postmenopausal women may have lower vitamin D levels, as the decline in estrogen affects the expression of vitamin D receptors.